Almost always one of four causes, in rough order of likelihood: missing authentication records (SPF/DKIM/DMARC), a sending domain or its links on a blacklist, volume behavior that looks bot-like (new domain, sudden bursts), or content-plus-engagement history that filters have learned to distrust.
Diagnose before guessing: run your domain through a deliverability check (ours is free and takes seconds) — it shows authentication and blacklist status immediately, which rules the big causes in or out.
Then fix in order: records first, list hygiene second (bounces poison reputation), volume discipline third. Content tweaks — the thing everyone fiddles with first — matter least until the plumbing is right.